Abstracts Results

All Abstracts for HRC 2010 have now been marked. See below for selected Abstracts.

If you have not received a confirmation e-mail, your Abstract has not been selected on this occasion.

Young Investigators Competition
Tuesday 5th October 13:30 - 17:15

The winner will be announced at the HRC 2010 Gala Dinner on Tuesday 5th October.

Chair: Dr G Andre Ng, Leicester
Judging Panel: Dr Michael Gammage, Birmingham;  Dr G Andre Ng, Leicester;  Prof Nicholas Peters, London; Prof Andrew Rankin, Glasgow.
Additional Abstract Markers: Dr Tim Betts, Oxford; Dr Sabine Ernst, London; Dr Andrew Grace, Cambridge; Dr Pier Lambiase, London.

1. FZ Khan
A Systematic Assessment of the Optimal Left Ventricular Pacing Site during Cardiac Resynchronization Therapy: An Initial Derivation of a Novel Non Invasive Method and Subsequent Validation with a Randomized Controlled Trial

2. MR Ginks
Computerised modelling accurately predicts acute response to CRT: initial results from a patient-specific biophysical model

3. KCK Wong
Balloon occlusion of the coronary sinus facilitates mitral isthmus ablation

4. SA Cooper
Heterogeneity of Fibrosis in the Infarct Border Zone Correlates with Arrhythmia Inducibility Post-Myocardial Infarction

5. P Saravanan
Omega 3 fatty acid supplementation alters expression levels of calcium handling proteins in human cardiomyocytes

6. KE Brack
The increase in nitric oxide and antifibrillatory effect of postganglionic vagal fibres is preserved during VIP inhibition and does not involve the endothelium

Oral Abstracts 1
Monday 4th October 13:30 - 17:15

AF Ablation

7. M MacDonald

Pulmonary vein isolation for persistent atrial fibrillation in patients with severe heart failure: a randomised controlled trial

8. L Malcolme-Lawes
Ganglionated plexi stimulation produces vagally mediated local changes in atrial fibrillation cycle length

9. KCK Wong
Coronary sinus diameter predicts difficult mitral isthmus ablation

10. S Page
Catheter ablation for atrial fibrillation on uninterrupted warfarin is safe and cost-effective

11. E Duncan
Robotic AF ablation - is there a learning curve?

12. L Malcolme-Lawes
Robotic ablation reduces local electrogram amplitude more than Manual ablation

Cardiovascular Implantable Electronic Devices

13. PA Scott
Scar Quantification Assessed by Contrast-Enhanced MRI Predicts Spontaneous Ventricular Arrhythmias In patients with Coronary Artery Disease and Implantable Cardioverter Defibrillators

14. F Gao
ICD lead-generator manufacturer ‘mismatch’ may cause unacceptable patient morbidity

15. SG Duckett
Advanced image fusion to overlay coronary sinus anatomy and myocardial scar with real time fluoroscopy to aid left ventricular lead implantation during CRT

16. A Arujuna
A single centre coronary sinus lead extraction

17. DHJ Elder
Longterm survival in patients with pacemakers for bradycardia

18. N Sulke
Immediate use of a remotely monitored ILR in diagnosing unexplained syncope: The Second Eastbourne Syncope Assessment Study (EaSyAS ll)

Oral Abstracts 2
Monday 4th October 13:30 - 17:15

Clinical Electrophysiology

19. M Rosenqvist
The Realise-AF registry: An international, observational, cross-sectional survey describing characteristics, cardiovascular risk, and management of patients with Atrial Fibrillation

20. AB Gopalamurugan
Catheter ablation in patients with d-transposition of great arteries – Outcomes, recurrence rate and predictors of recurrence of tachyarrhythmias

21. NK Kelland
Safety & efficacy of combining substrate & activation guided ablation of  Ventricular Tachycardia (VT) in patients with structural heart disease

22. NK Kelland
Micro-re-entry in dilated left upper pulmonary veins: a distinct clinical syndrome in AF patients

23. VA Ezzat
The Atrial Fibrillation Patient Journey – Patient Satisfaction from a Single Centre UK Experience

24. MC Finlay
Conduction delay in desmoplakin mutation positive patients: electrical manifestations of sub-clinical disease demonstrated by non-contact mapping

Basic Science

25. FS Ng
Conduction Slowing in the Infarct Border Zone Correlates with Ventricular Arrhythmia Inducibility in a Chronic Myocardial Infarction Model

26. FS Ng
ZP1210 attenuates gap junctional uncoupling and conduction slowing in a metabolic stress model – An Optical Mapping study

27. AA Owusu-Agyei
The Gap Junction Modulator ZP1210 Attenuates Ischaemia-Induced Connexin43 Dephosphorylation

28. J Winter
Inotropic enhancement during cardiac contractile modulation is associated with a shortening of epicardial action potential duration and is prevented through pharmacological β1 adrenoceptor blockade in the isolated rabbit heart

29. KE Brack
A non-cholinergic NO release and NO-dependent anti-fibrillatory effect of vagal efferent stimulation on the cardiac ventricle

30. CA Martin
Multi-Array Mapping Demonstrates both Conduction Delay and Repolarization Abnormalities in a Mouse Model of Brugada Syndrome

Featured Posters
Monday 4th October 17:30 - 19:00
Exhibition - Monarch Suite

31. MR MacDonald
Radiofrequency ablation of persistent atrial fibrillation in patients with heart failure and severe left ventricular dysfunction: patient characteristics and procedural success rates from a randomised controlled trial

32. EL Berry & HC Padgett
Incidence screening of patients following ST Elevation Myocardial Infarction for Primary Prevention ICD implantation has a low therapeutic yield

33. PA Scott
The Use of Biomarkers to Refine Patient Selection For ICD therapy

34. I Chung
Impact of Advanced Age on Survival in Patients with Implantable Cardioverter Defibrillators- Does Age Matter?

35. AK Shetty
Initial single centre experience with a novel quadripolar lead for cardiac resynchronisation therapy

36. PWX Foley
Effect of pacing myocardial scar in patients undergoing cardiac resynchronisation therapy assessed using gadolinium-enhancement cardiovascular magnetic resonance

37. ME Bull
Professional Support Needs of Patients with Atrial Fibrillation

38. JS Ware
A new quantitative trait locus for heart rate in the rat

39. LTM Yung
A comparison of Mobile Cardiac Telemetry Systems (MCT) with conventional cardiac monitoring for the investigation of common conditions suggestive of cardiac arrhythmias

Moderated Posters 1
Monday 4th October 12:45 - 13:15
Monarch Suite Foyer

40. AK Shetty
Real-time cardiac MR overlay guided left ventricular lead placement predicts acute response to CRT

41. MR Ginks
A Simultaneous X-MR and Non-Contact Mapping Study of the Acute Haemodynamic Effect of Left Ventricular Endocardial and Epicardial Cardiac Resynchronisation Therapy in Humans

42. SG Duckett
CMR & 3D Echo Derived Systolic Dyssynchrony Index to Predict Acute Haemodynamic Response to LV and BIV Pacing in Patients Awaiting CRT

43. SA Niederer
Length-Dependent Tension in the Failing Heart and the Efficacy of Cardiac Resynchronisation Therapy

44. DHJ Elder
Betablockers are associated with improved survival in patients with pacemakers for bradycardia

45. RC Bond
Pacemaker Complications in a DGH

46. WB Nicolson
What has changed: Reduction in mortality following revision of NICE guidance?

47. NJ Linker
When should an implantable loop recorder be used in the diagnosis of syncope? Results from the PICTURE study

Moderated Posters 2
Tuesday 5th October 12:45 - 13:15
Monarch Suite Foyer

48. N Sulke
Prodrome in syncope: A predictor of cause?

49. JC Gomes
Desmoplakin haploinsufficiency is a purely electrical disease: in vivo and in vitro models of arrhythmogenic right ventricular cardiomyopathy

50. C Sawh
The Safety And Efficacy Of Anti-arrhythmic Drugs In The Management Of Acute Atrial Fibrillation

51. K Chima
Management of atrial fibrillation in a NICE way - a retrospective audit

52. PA Venables
3.75 frames per second fluoroscopy safely minimises radiation exposure during EP procedures

53. JL Salinet Jr
The Spatial and Temporal Variability of the 3D Dominant Frequency Mapping from 2048 Non-Contact Unipolar Electrograms in Human Atrial Fibrillation

54. PA Venables
Pulmonary Vein Pacing to Prove Exit-Block with Ablation Frontiers PVAC: Threshold Testing, A Simple Method for Identification of Far Field Capture

55. KCK Wong
Incidence of Recovered Conduction Following Previously Successful Linear Ablations

Posters 1
Monday 4th October
Displayed for 1 day in the HRC Exhibition
Authors will be available for questions 10:15 - 10:45

56. PA Scott
Transseptal Left Ventricular Endocardial Pacing Reduces Dispersion of Ventricular Repolarization

57. J Tenkorang
Long-term intermittent atrial tachycardia decreases activation recovery interval, flattens its kinetics and blunts its rate dependence before sustained atrial fibrillation

58. JC Caldwell
Outcomes of evaluation of relatives with a family history of young sudden cardiac death; nearly as many ICDs removed as implanted

59. A Adlan
Continuation of warfarin during pacemaker and implantable defibrillator procedures is associated with low rates of bleeding complications

60. K Gregory
1 Month Extended External Loop Recorder (ELR) Reduces the Rate of Implantable Loop Recorder (ILR) Use

61. RJ Hunter
Left Atrial Wall Stress Distribution in Patients with AF and the Relationship with Electrophysiologic Abnormalities

62. R Ang
Impact of Variant Pulmonary Vein Anatomy on Long Term Outcome After Catheter Ablation of AF

63. LI Svintosa
Treatment experience of tachyarrhythmias starting in antenatal period

64. JD Jones
Upgrading to a Biventricular Device: Real Life Data from a High Volume Centre

65. SJ Podd
Atrial fibrillation ablation in a district general hospital – 2 years experience

Posters 2
Tuesday 5th October
Displayed for 1 day in the HRC Exhibition
Authors will be available for questions 10:15 - 10:45

66. SJ Podd
Does a Bluetooth remotely monitored ILR improve diagnostic efficacy and outcome compared to ‘standard’ ILR?

67. P Saravanan
Relationship between expression levels of atrial connexins, P wave dispersion and risk of post-operative atrial fibrillation following CABG

68. PWX Foley
Diagnostic yield of implantable loop recorders

69. C O'Mahony
The incidence and determinants of internal cardioverter defibrillator implant related complications in hypertrophic cardiomyopathy

70. A Patwala
A single centre experience with Sprint Fidelis lead revisions

71. CM Plymen
The Relationship between QRS Duration and NT-Pro Brain Natriuretic Peptide to Arrhythmia Burden in Adults with a Systematic Right Ventricle

72. DG Jones
Effect of linear ablation on complex fractionation at remote atrial sites: observations from sequential high density mapping of persistent AF

73. A Arujuna
Transvenous Lead Extraction: Outcomes, Trends and Changing Indications Over the Last Decade

74. PD Brown
Assessing the Possibility of Positioning Electrophysiology Catheters in the Heart using a New Remote Controlled Robotic Catheter Manipulation System - Efficacy and Feasibility Study

75. S Yusuf
Cavo-Tricuspid Isthmus Ablation for Type 1 Atrial Flutter using the New Amigo Remote Catheter Manipulation System